Table 1.
Extended pedigree-based sequencing studies of psychotic or affective disorders
| Reference | Year published | Ascertainment | sequence | # of families | Individuals sequenced | Populationa | Findings replicated |
|---|---|---|---|---|---|---|---|
| Bouwkamp [109] | 2017 | Bipolar disorder | WGS | 1 | 1 | Dutch | No |
| Hornig [151] | 2017 | Schizophrenia | Exome | 1 | 8 | German | No |
| John [152] | 2017 | Schizophrenia | Exome | 1 | 4 | Indian | Partial |
| Rao [153] | 2017 | Bipolar disorder | Exome | 4 | 9 | USA | No |
| Steinberg [105] | 2017 | Schizophrenia | WGS | 1 | 7 | Icelandic | Yes |
| Zhang [154] | 2017 | Bipolar disorder | Exome | 1 | 6 | USA | No |
| Egawa [155] | 2016 | Schizophrenia | Exome | 1 | 3 | Japanese | No |
| Goes [156] | 2016 | Bipolar disorder | Exome | 8 | 36 | USA | No |
| Homann [106] | 2016 | Schizophrenia | WGS | 9 | 90 | USA | No |
| Kos [157] | 2016 | Schizophrenia | Exome | 8 | 134 | USA | No |
| Subaran [158] | 2016 | Major depression | Exome | 5 | 12 | USA | No |
| Watanabe [159] | 2016 | Schizophrenia | Exome | 3 | 12 | Japanese | Partial |
| Zhou [160] | 2016 | Schizophrenia | Exome | 1 | 4 | Chinese | No |
| Ament [161] | 2015 | Bipolar disorder | WGS | 41 | 200 | Amish | No |
| Kember [162] | 2015 | Bipolar disorder | WGS | 1 | 80 | Amish | Yes |
| Thygesen [163] | 2015 | Schizophrenia | WGS | 6 | 3 | Dane | No |
| Georgi [142] | 2014 | Bipolar disorder | WGS | 1 | 50 | Amish | No |
| Strauss [164] | 2014 | Bipolar disorder | Exome | 4 | 26 | Amish | No |
| Timms [107] | 2013 | Schizophrenia | Exome | 5 | 12 | USA | No |
a
Studies conducted in the USA involved subjects of European Ancestry