Table 3.
Stepwise linear regression models between DNAm at NEGR1 gene locus and childhood developmental outcomes.
BMI-z (β ± SE; p-value) | |
---|---|
cg26153364 | −0.16 ± 0.04; p = 0.008 |
cg23166710 | 0.14 ± 0.08; p = 0.03 |
Model R square | 0.042 |
Model p value | 0.003 |
SDQ total score (β ± SE, p-value) | |
cg04932878 | 0.22 ± 1.0; p = 1.3x10−4 |
cg16525738 | −0.14 ± 0.18; p = 0.01 |
cg23166710 | −0.13 ± 0.36; p = 0.04 |
Model R square | 0.073 |
Model p value | 1.3x10−4 |
SE, standard error; DNAm, DNA methylation; NEGR1, neuronal growth regulator 1; SDQ, Strengths and Difficulties Questionnaire; BMI-z, z-score body mass index