Table 1.
Blood |
IC50 |
Bone |
IC50 |
Breast |
IC50 |
Colorectum |
IC50 |
Esophagus |
IC50 |
AMO1 | 0.387 | HOS | 3.953 | MCF7 | 2.623 | LS513 | 0.825 | KYSE270 | 1.186 |
MOLP8 | 3.121 | U2OS | 6.06 | DU4475 | 3.495 | T84 | 0.909 | KYSE70 | 6.428 |
L363 | 3.391 | CADOES1 | 6.879 | MDAMB468 | 4.613 | SW948 | 1.089 | TE1 | 8.155 |
RPMI8226 | 4.075 | A673 | 7.411 | BT549 | 6.341 | SW837 | 1.117 | KYSE410 | 8.715 |
KMS11 | 6.546 | SAOS2 | 37.74 | T47D | 10.114 | LOVO | 1.146 | OE19 | 27.192 |
U266B1 | 18.137 | MDAMB453 | 10.922 | HT29 | 1.303 | ||||
LP1 | 20.263 | MDAMB436 | 14.05 | HCT116 | 1.429 | ||||
MDAMB361 | 25.022 | HCT15 | 2.667 | ||||||
MDAMB231 | 31.838 | RKO | 2.698 | ||||||
MDAMB415 | 222.14 | COLO205 | 3.852 | ||||||
SW1417 | 6.169 | ||||||||
LS123 | 74.541 | ||||||||
Mean |
7.989 |
Mean |
12.409 |
Mean |
33.116 |
Mean |
8.145 |
Mean |
10.335 |
Kidney |
IC50 |
Liver |
IC50 |
Lung |
IC50 |
Ovary |
IC50 |
Pancreas |
IC50 |
A498 | 0.922 | HUCCT1 | 5.073 | CALU6 | 0.675 | A2780 | 1.248 | BXPC3 | 2.808 |
OSRC2 | 2.201 | HEPG2 | 1.668 | NCIH460 | 1.662 | ES2 | 2.238 | KP4 | 3.381 |
CAKI2 | 4.314 | NCIH2052 | 3.926 | A549 | 2.301 | IGROV1 | 2.36 | CAPAN1 | 3.758 |
786O | 6.334 | HLF | 13.711 | NCIH526 | 4.322 | OVCAR8 | 6.249 | MIAPACA2 | 4.356 |
SNU182 | 44.587 | NCIH520 | 5.042 | CAOV3 | 14.731 | SW1990 | 4.727 | ||
NCIH69 | 5.504 | NIHOVCAR3 | 20.333 | ASPC1 | 8.235 | ||||
DMS53 | 5.835 | SKOV3 | 73.75 | CFPAC1 | 16.033 | ||||
NCIH23 | 6.184 | ||||||||
NCIH446 | 7.117 | ||||||||
NCIH358 | 7.197 | ||||||||
NCIH1792 | 7.441 | ||||||||
SKMES1 | 9.8 | ||||||||
NCIH1703 | 10.225 | ||||||||
NCIH1299 | 10.252 | ||||||||
EBC1 | 11.634 | ||||||||
NCIH522 | 14.095 | ||||||||
NCIH1373 | 15.418 | ||||||||
SKLU1 | 17.054 | ||||||||
HCC4006 | 25.101 | ||||||||
NCIH1048 | 35.987 | ||||||||
NCIH441 | 49.553 | ||||||||
NCIH1648 | 59.687 | ||||||||
Mean |
3.443 |
Mean |
13.793 |
Mean |
14.186 |
Mean |
17.273 |
Mean |
6.185 |
Pharynx |
IC50 |
Prostate |
IC50 |
Salivary glands |
IC50 |
Skin |
IC50 |
Soft tissue |
IC50 |
DETROIT562 | 5.849 | LNCAPCLONEFGC | 1.72 | A253 | 3.877 | SKMEL5 | 1.614 | HT1080 | 2.363 |
FADU | 7.005 | PC3 | 5.247 | SKMEL28 | 3.503 | SKUT1 | 4.716 | ||
22RV1 | 6.565 | A375 | 5.521 | A204 | 7.2 | ||||
A2058 | 7.49 | ||||||||
Mean |
6.427 |
Mean |
4.511 |
Mean |
3.877 |
Mean |
4.532 |
Mean |
4.76 |
Stomach |
IC50 |
Thyroid |
IC50 |
Tongue |
IC50 |
Urethra |
IC50 |
Uterus |
IC50 |
AGS | 0.287 | TTTHY | 7.816 | CAL27 | 2.714 | RT4 | 0.519 | AN3CA | 1.031 |
NUGC4 | 1.99 | SW579 | 19.97 | SCC25 | 16.844 | SW780 | 2.596 | ||
SNU1 | 2.112 | SCC4 | 25.945 | 5637 | 9.124 | ||||
SNU601 | 2.172 | SCC9 | 35.39 | RT11284 | 10.092 | ||||
SNU668 | 2.343 | SCC15 | 77.209 | HT1376 | 18.702 | ||||
HGC27 | 2.891 | ||||||||
SNU719 | 3.384 | ||||||||
MKN1 | 3.584 | ||||||||
SNU5 | 3.784 | ||||||||
OCUM1 | 6.832 | ||||||||
SNU216 | 7.426 | ||||||||
Mean | 3.346 | Mean | 13.893 | Mean | 31.62 | Mean | 2.438 | Mean | 1.031 |
Abbreviations: IC50, inhibitory concentration 50%.