Figure 3.

The serum FGF23 levels are useful for the detection of CKD and its complications. (a) An ROC curve of FGF23 was constructed for the diagnosis of CKD. (b) Serum bone-specific alkaline phosphatase and (c) hemoglobin concentrations are shown in patients with measurements above or below the cut-off value (43.1 pg/mL) of serum FGF23 determined by an ROC analysis. (d) The AUC of the ROC curve generated by a multivariable logistic regression analysis using both FGF21 and FGF23 was significantly larger than the one generated by FGF21 alone.