Table 5.
Multivariable Linear Regression Analysis.
| Variables | β | (95% CI) | t | p value | ||||
|---|---|---|---|---|---|---|---|---|
| logFGF19 (adjusted R-squared: 0.19) | ||||||||
| ALT | -0.012 | -0.015 to -0.0081 | -3.2 | 0.002** | ||||
| Cardiovascular disease (complication) | 0.19 | 0.10 to 0.28 | 2.1 | 0.036* | ||||
| Active vitamin D3(medication) | 0.23 | 0.15 to 0.32 | 2.9 | 0.005** | ||||
| logFGF21 (adjusted R-squared: 0.29) | ||||||||
| eGFRcys | -0.0037 | -0.0053 to -0.0021 | -2.3 | 0.025* | ||||
| TG | -0.0018 | -0.0024 to -0.0012 | 2.9 | 0.005** | ||||
| Hypertension | 0.15 | 0.081 to 0.22 | 2.1 | 0.036* | ||||
| logFGF23 (adjusted R-squared: 0.40) | ||||||||
| 1,25-dihydroxy vitamin D3 | -0.0020 | -0.0027 to -0.0014 | -3.2 | 0.002** | ||||
| eGFRcys | -0.0031 | -0.0039 to -0.0024 | -4.4 | <0.001*** | ||||
| TRACP5b | -0.00019 | -0.00027 to -0.00011 | -2.4 | 0.020* |
*p<0.05, **p<0.01, ***p<0.001
FGF19 model included age, sex, osteoporosis, Alb, BW, and metformin; FGF21 model included age, sex, BMI, FPG, HDL and PPI; FGF23 model included age, sex, BAP, intact PTH and P1NP, which were all excluded in the final model by p value stepwise.