Table 2.
Patient Characteristics in IgA Nephropathy (IgAN), Membranous Nephropathy (MN) and Tubulointerstitial Nephritis (TIN).
| IgAN | MN | TIN | ||||
|---|---|---|---|---|---|---|
| Age, year | 48.6±18.0 | 68.8±12.6* | 66.4±7.1** | |||
| Sex (Male / Female) | 12 / 19 | 1 / 4 | 0 / 5 | |||
| Height (cm) | 162.8±10.4 | 159.0±4.3 | 156.0±3.8* | |||
| Body weight (kg) | 56.4±10.5 | 52.6±6.9 | 48.6±7.3 | |||
| Body mass index (kg/m2) | 21.2±3.0 | 20.8±2.2 | 20.0±3.6 | |||
| Systolic BP (mmHg) | 116.2±13.1 | 117.8±17.6 | 123.4±27.4 | |||
| Diastolic BP (mmHg) | 72.3±10.0 | 67.8±12.7 | 75.2±11.1 | |||
| Heart rate (/min) | 65.7±6.1 | 65.6±8.3 | 69.2±13.0 | |||
| sCr (mg/dL) | 0.88±0.22 | 0.90±0.36 | 1.82±0.51*, # | |||
| eGFR (mL/min/1.73m2) | 69.1±18.6 | 58.0±20.5 | 24.1±7.6**, # | |||
| Plasma Ang II (pg/mL) | 11.8±4.5 | 7.6±3.1 | 14.8±11.8 | |||
| Log u-Alb/day (mg/day) | 2.48±0.43 | 3.29±0.48* | 1.64±0.49*, ## | |||
| Log u-Alb/Cr (μg/mg) | 2.45±0.50 | 3.35±0.51** | 1.74±0.49*, ## | |||
| Log u-AGT/day (ng/day) | 4.69±0.51 | 5.61±1.04 | 6.00±0.60* | |||
| Log u-AGT/Cr (ng/mg) | 1.66±0.56 | 2.67±1.05** | 3.10±0.61** | |||
| Log u-AGT/Alb (ng/mg) | 2.21±0.35 | 2.32±0.58 | 4.36±0.19**, ## | |||
| Log u-α1MG (mg/L) | 0.73±0.35 | 1.27±0.48 | 1.83±0.33** | |||
| Interstitial fibrosis (%) | 21.4±15.3 | 18.0±16.8 | 60.0±25.2# |
BP: blood pressure, sCr: serum creatinine, eGFR: estimated glomerular filtration rate, Ang II: angiotensin II, u-Alb/day: urinary albumin/day, u-Alb/Cr: urinary albumin to creatinine ratio, u-AGT/day: urinary angiotensinogen/day, u-AGT/Cr: urinary angiotensinogen to creatinine ratio, u-AGT/Alb: urinary angiotensinogen to urinary albumin ratio, u-α1MG: urinary alpha 1 microglobulin
*p<0.05 and **p<0.01 versus IgA nephropathy and#p<0.05 and##p<0.01versus membranous nephropathy