Figure 3.

(a) SERS chromatograms of 2 replicate LC-SERS runs of a MMTV-Wnt1 sample (CN466) using isocratic mobile phase (method II, supplementary materials). (b) A Pearson’s cross-correlation was used to determine matched signals in both replicate SERS chromatogram. The signals were considered to match when spectra in each replicate satisfied the following constraints: (1) Corr. Coef. > 0.5; (2) elution time difference < 10 seconds (spectral index difference < 50). The gray bars highlight matched signals.