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. Author manuscript; available in PMC: 2021 Feb 17.
Published in final edited form as: Analyst. 2020 Feb 17;145(4):1087–1102. doi: 10.1039/c9an01925a

Table 1.

Figures of merit of major electroanalytical techniques for neurotransmitter detection

Techniques Sensitivity Selectivity Temporal resolution
Amperometry low (25–100 nM LOD dopamine but sufficient to count number of molecules)20 low (All compounds that can be oxidized or reduced at the applied potential will give the signal.) highest (electronic sampling rate, < 1 ms) 2

Pulse Voltammetry high (10 nM LOD dopamine)20 high (Molecules with oxidation potential differs more than 100 mV is resolved.)2 low (up to 1 min)

Fast-Scan Cyclic Voltammetry high (10 nM LOD dopamine)20 highest (CV shape identifies molecule, but similar species may have similar CV.) high (triangular waveform frequency, 100 ms)