Table 1.
Figures of merit of major electroanalytical techniques for neurotransmitter detection
| Techniques | Sensitivity | Selectivity | Temporal resolution |
|---|---|---|---|
| Amperometry | low (25–100 nM LOD dopamine but sufficient to count number of molecules)20 | low (All compounds that can be oxidized or reduced at the applied potential will give the signal.) | highest (electronic sampling rate, < 1 ms) 2 |
| Pulse Voltammetry | high (10 nM LOD dopamine)20 | high (Molecules with oxidation potential differs more than 100 mV is resolved.)2 | low (up to 1 min) |
| Fast-Scan Cyclic Voltammetry | high (10 nM LOD dopamine)20 | highest (CV shape identifies molecule, but similar species may have similar CV.) | high (triangular waveform frequency, 100 ms) |