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Quantitative metrics compared among the WM of healthy controls, NAWM of patients with MS, and WM lesions of patients with MS. The median and 25th and 75th percentiles are marked in boxplots, with outliers plotted by open circles. Asterisks indicate significant differences among the groups. The asterisk indicates P < .05; double asterisks, P < .01; triple asterisks, P < .001.
