Fig 3.

Example of a grade 2 DWI-FLAIR ATL severity from uremia. A previously healthy 16-year-old boy with coma had renal failure of unknown cause, blood urea nitrogen level of >115 mg/dL (normal <25 mg/dL), creatinine level of 18.34 mg/dL (normal, <1.2 mg/dL), glomerular filtration rate of 5 (normal, >90), and systolic blood pressure of >160 mm Hg. MR imaging revealed PVWM abnormalities sparing the basal ganglia on DWI (A and B), with a normal appearance on FLAIR (C) and normal MRA (not shown). Laboratory work-up only revealed uremia. Clinically, the symptoms resolved with dialysis, and MR imaging 2 days later (not shown) noted continued diffusion reduction, while the ADC values rose with complete resolution of symptoms (the ATLOS and mRS scores were 0).