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. 2020 Feb 12;11:74. doi: 10.3389/fphys.2020.00074

TABLE 1.

Pregnancy outcomes of day 3, day 5, day 6, and day 7 vitrified-warmed embryo transfer groups.

Day 3 (n = 8591) Day 5 (n = 1961) Day 6 (n = 4910) Day 7 (n = 413) P-valuea P-valueb P-valuec
Clinical pregnanciesd 4313/8591 (50.2) 1194/1961 (60.9) 2685/4910 (54.7) 136/413 (32.9) <0.001 <0.001 <0.001
Miscarriages 569/4313 (13.2) 174/1194 (14.6) 467/2685 (17.4) 26/136 (19.1) 0.046 0.160 0.605
1st trimester 496/4313 (11.5) 152/1194 (12.7) 414/2685 (15.4) 24/136 (17.6) 0.028 0.109 0.484
2st trimester 73/4313 (1.7) 22/1194 (1.8) 53/2685 (2.0) 2/136 (1.5) 0.843 0.758 0.679
Ectopic 125/4313 (2.9) 24/1194 (2.0) 21/2685 (0.8) 0/136 (0) 0.033 0.163 0.622
Live birthsd 3608/8591 (42.0) 994/1961 (50.7) 2193/4910 (44.7) 110/413 (26.6) <0.001 <0.001 <0.001
Stillbirths 11/3608 (0.3) 2/994 (0.2) 4/2193 (0.2) 0/413 (0) 0.617 0.362 0.385

Clinical pregnancy was diagnosed by the ultrasonographic visualization of one or more gestational sac after embryo transfer; Miscarriage rate was defined as a loss of clinical pregnancy before the 20th gestational week; Data are were presented as numbers and proportion (%). aP-value for day 3 vs. day 7. bP-value for day 5 vs. day 7. cP-value for day 6 vs. day 7. dInclusion of single and twin pregnancies.