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. 2020 Feb 12;11:74. doi: 10.3389/fphys.2020.00074

TABLE 2.

Patient and cycle characteristics of the matched day 3, day 5, day 6, and day 7 vitrified-warmed embryo transfer groups.

Characteristics Day 3 Day 5 Day 6 Day 7 P-valuea P-valueb P-valuec
Age (years) 32 (29, 34) 31 (28, 34) 32 (29, 35) 31 (29, 34) 0.876 0.601 0.931
BMI (kg/m2) 21.0 (19.5, 22.9) 20.8 (19.5, 22.6) 20.8 (19.5, 22.5) 20.7 (19.6, 22.6) 0.632 0.986 0.875
Duration of infertility (years) 3 (2, 5) 3 (2, 5) 3 (2, 5) 3 (2, 5) 0.570 0.741 0.785
Gravidity 0 (0, 1) 0 (0, 1) 0 (0, 1) 1 (0, 1) 0.643 0.837 0.723
Parity 0 (0, 0) 0 (0, 0) 0 (0, 0) 0 (0, 0) 0.901 0.918 0.845
FET rank
 First 196 (70.3) 195 (69.9) 183 (65.6) 65 (69.9) 0.948 1 0.446
 Higher rank 83 (29.7) 84 (30.1) 96 (34.4) 28 (30.1)
Main infertility cause (%) 0.647 0.882 0.830
 Female 145 (52.0) 157 (56.3) 157 (56.3) 50 (53.8)
 Male 47 (16.8) 29 (10.4) 38 (13.6) 11 (11.8)
 Mixed 67 (24.0) 80 (28.7) 65 (23.3) 26 (28.0)
 Other 20 (7.2) 13 (4.7) 19 (6.8) 6 (6.5)
Endometrial preparation (%) 0.526 0.887 0.440
 Natural cycles 64 (22.9) 71 (25.4) 87 (31.2) 26 (28.0)
 Hormone therapy cycles 121 (43.4) 107 (38.4) 85 (30.5) 35 (37.6)
 Stimulated cycles 94 (33.7) 101 (36.2) 107 (38.4) 32 (34.4)
Cycles with ICSI (%) 127 (45.5) 129 (46.2) 123 (44.1) 43 (46.2) 0.904 1 0.718
Endometrial thickness on ET day (mm) 10.3 (9.1, 11.9) 10.3 (9.2, 11.8) 10.5 (9.1, 12.1) 10.2 (9.1, 12.3) 0.738 0.797 0.872
No. of embryo transferred 0.673 0.630 0.904
 1 157 (56.3) 158 (56.6) 148 (53.0) 50 (53.8)
 2 122 (43.7) 121 (43.4) 131 (47.0) 43 (46.2)
Year of treatment (%) 0.770 0.438 0.863
 2006–2011 74 (26.5) 66 (23.7) 77 (27.6) 28 (30.1)
 2012–2013 75 (26.9) 87 (31.2) 79 (28.3) 25 (26.9)
 2014–2017 130 (46.6) 126 (45.2) 123 (44.1) 40 (43.0)

FET, frozen embryo transfer. ET, embryo transfer. Data are presented as mean (±SD) or median (first quartile, third quartile) according to if variables were normally distributed or not. Continuous variables were compared using t-test or Mann–Whitney–Wilcoxon tests, and categorical variables were presented as numbers (%) and evaluated with Chi-squared tests. aP-value for day 3 vs. day 7. bP-value for day 5 vs. day 7. cP-value for day 6 vs. day 7.