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. 2020 Feb 12;8:81. doi: 10.3389/fchem.2020.00081

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Copyright © 2020 Wu, Lou and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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2D ligand-protein interaction of Riluzole (A) and CyPPA analog 1 (B) at PSK2 binding site. The pink arrow is referred to hydrogen bond. The red line is referred to Pi-cation interaction.