Table 5.
Symptoms reported by enrolled Associates by age (adult = age ≥ 18 years, child = age ≤ 18 years), among those with symptomatic infections (defined as the presence of any solicited symptom) in Thailand.
| Thailand | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total—by age | Total—by serology* | Primary | Secondary | |||||||||
| Child | Adult | p-value | 1o | 2o | p-value | Child | Adult | p-value | Child | Adult | p-value | |
| # Dengue illnesses** | 163 | 140 | NA | 32 | 238 | NA | 17 | 15 | NA | 129 | 109 | NA |
| Asymptomatic | 13.5% | 38.6% | <0.001 | 37.5% | 21.4% | 0.044 | 17.6% | 60.0% | 0.027 | 10.9% | 33.9% | <0.001 |
| Hospitalized | 21.5% | 7.9% | <0.001 | 3.1% | 18.5% | 0.024 | 5.9% | 0.0% | 1.000 | 25.6% | 10.1% | 0.002 |
| Fever | 80.4% | 51.4% | <0.001 | 59.4% | 69.3% | 0.312 | 76.5% | 40.0% | 0.070 | 82.9% | 53.2% | <0.001 |
| Headache | 56.4% | 42.1% | 0.016 | 15.6% | 56.7% | <0.001 | 11.8% | 20.0% | 0.645 | 65.9% | 45.9% | 0.002 |
| Rhinorrhea | 30.1% | 6.4% | <0.001 | 15.6% | 20.6% | 0.641 | 23.5% | 6.7% | 0.338 | 31.8% | 7.3% | <0.001 |
| Cough | 35.6% | 15.0% | <0.001 | 15.6% | 28.6% | 0.141 | 11.8% | 20.0% | 0.645 | 39.5% | 15.6% | <0.001 |
| Anorexia | 46.6% | 26.4% | <0.001 | 18.8% | 39.9% | 0.020 | 23.5% | 13.3% | 0.659 | 51.2% | 26.6% | <0.001 |
| Nausea/vomiting | 42.3% | 19.3% | <0.001 | 6.3% | 33.6% | 0.001 | 11.8% | 0.0% | 0.486 | 45.0% | 20.2% | <0.001 |
| Drowsiness | 30.7% | 21.4% | 0.089 | 6.3% | 29.4% | 0.005 | 53.1% | 46.9% | 0.212 | 34.9% | 22.9% | 0.047 |
| Muscle/joint pain | 38.7% | 45.7% | 0.243 | 15.6% | 47.5% | 0.001 | 5.9% | 26.7% | 0.161 | 47.3% | 47.7% | 1.000 |
| Abdominal pain | 27.0% | 11.4% | 0.001 | 6.3% | 23.1% | 0.035 | 0.0% | 13.3% | 0.212 | 32.6% | 11.9% | <0.001 |
| Rash | 12.3% | 7.9% | 0.255 | 9.4% | 11.3% | 1.000 | 17.6% | 0.0% | 0.229 | 13.2% | 9.2% | 0.413 |
| Diarrhea | 19.6% | 11.4% | 0.059 | 9.4% | 16.4% | 0.437 | 11.8% | 6.6% | 1.000 | 20.2% | 11.9% | 0.113 |
| Retroorbital pain | 17.8% | 24.3% | 0.201 | 9.4% | 21.8% | 0.158 | 5.9% | 13.3% | 0.589 | 20.9% | 22.9% | 0.754 |
| Bleeding | 6.7% | 2.9% | 0.183 | 0.0% | 5.9% | 0.386 | 0.0% | 0.0% | NA | 8.5% | 2.8% | 0.094 |
*
Of those with serologically-confirmed DENV infection (i.e., either primary or secondary DENV infection).
**
Among all those with confirmed DENV infection (i.e., whether symptomatic or asymptomatic).
P-values < 0.05 indicate statistically significant comparisons, applying Mantel-Haenszel chi-squared testing.
NA indicates not applicable.