Figure 1.

The clinical relevance of increased BRD4 mRNA and protein expression in GIST. A, Real‐time PCR of GIST demonstrated significantly increased BRD4 mRNA abundance in higher risk categories using NCCN guidelines. B, The level of BRD4 in representative low‐, moderate‐ and high‐risk GIST was analysed by IHC staining. C, Real‐time PCR of GIST demonstrated significantly increased BRD4 mRNA abundance in higher risk categories using NCI guidelines. D, In log‐rank analyses, BRD4 overexpression was highly predictive of poor disease specific survival. *P < .05