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. 2020 Jan 19;24(4):2519–2530. doi: 10.1111/jcmm.14945

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© 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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JQ1 enhances the antitumour effect of imatinib in vivo. A, GIST430‐derived xenograft was treated with JQ1 at indicated concentration. Tumour volume at indicated time points after treatment was calculated and plotted with P values. B, GIST430‐derived xenograft was treated with imatinib, JQ1, and their combination. Tumour volume at indicated time points after treatment was calculated and plotted with P values. C, The levels of indicated protein in randomly selected tumours were analysed by Western blotting. D, The level of indicated protein was analysed by IHC or IF staining. *P < .05