FIG 5.

Differentially expressed genes mapped on the proposed metabolic pathways of A. kawachii. The pathway was constructed based on the metabolic model of A. niger and A. nidulans (51, 54, 55). The glyoxylate shunt was placed in the mitochondria. Bold and dotted arrows indicate downregulated and upregulated reactions due to laeA disruption, respectively. Numbers (1 to 15) next to the arrows correspond to the numbering of locus tags in Table 1. Abbreviations: CoA, coenzyme A; DHA, dihydroxyacetone; DHAP, dihydroxyacetone phosphate; FAD, flavin adenine dinucleotide; Gln, glutamine; TP, transporter.