TABLE 1.
Citric acid production-related genes among up- and downregulated genes following laeA disruption
|
Reaction no. in Fig. 5 |
Locus tag | Putative function |
Log2 fold change |
FDR |
|---|---|---|---|---|
| 1 | AKAW_07170 | Fructose-bisphosphate aldolase | 4.01 | 0.0011 |
| 2 | AKAW_04737 | Glyceraldehyde 3-phosphate dehydrogenase | −1.05 | 0.0005 |
| 3 | AKAW_03026 | Phosphoglycerate mutase | −0.78 | 0.0335 |
| 4 | AKAW_00170 | Citrate synthase | −0.92 | 0.0014 |
| 5 | AKAW_06223 | Citrate synthase | −11.35 | 1.10E−98 |
| 6 | AKAW_07594 | Succinate-CoA ligase (GDP-forming) alpha chain | 1.27 | 0.0052 |
| 7 | AKAW_07352 | Succinate dehydrogenase | −0.71 | 0.0352 |
| 8 | AKAW_00119 | Isocitrate lyase | −1.40 | 1.063E−05 |
| 9 | AKAW_05189 | Alpha,alpha-trehalosephosphate synthase (UDP forming) 1 (TpsA, TpsB) | −0.76 | 0.0108 |
| 10 | AKAW_03597 | Alpha,alpha-trehalosephosphate synthase (UDP forming) 1 (TpsA, TpsB) | 0.87 | 0.0024 |
| 11 | AKAW_00489 | Ribose-5-phosphate isomerase (B) | 1.03 | 0.0035 |
| 12 | AKAW_08691 | Alcohol oxidase | 1.65 | 3.18E−09 |
| 13 | AKAW_02095 | Phosphoenolpyruvate carboxykinase (ATP) | 0.80 | 0.0139 |
| 14 | AKAW_00804 | Pyruvate carboxylase (cytosol) | −1.15 | 0.0168 |
| 15 | AKAW_06947 | Pyruvate decarboxylase | 0.83 | 0.0205 |