Table 1.

Genome-wide significant loci associate to celiac disease

CHR	BP (hg19)	SNP	Risk allele	Other allele	N	OR	P(WZ)	MAF in CEU population	Closest gene	Is the region associated to other IMDs?	All eQTLs
1	183532580	rs17849502a	T	G	7	1.43	<2.22 × 10–16	0.06	NCF2	SLE, CeD	none
3	69252899	rs6806528	T	C	8	1.19	9.10 × 10−09	0.13	FRMD4B		FRMD4B
12	6511996	rs2364484	C	A	6	1.13	5.31 × 10−09	0.28	RP1–102E24.8/ LTBR	AS, JIA, MS, PBC	LTBR
22	37633851	rs9610686	C	T	7	1.11	3.28 × 10−08	0.39	RAC2	T1D, VIT	C1QTNF6, SSTR3, CYTH4, RAC2

^aMissense variant, BP base pairs, N number of cohorts, OR odds ratio, P(WZ) weighted P value, SLE systemic lupus erythematosus, AS ankylosing spondylitis, JIA juvenile idiopathic arthritis, MS multiple sclerosis, PBC primary biliary cirrhosis, T1D type 1 diabetes and VIT vitiligo