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. 2020 Feb 18;10:2854. doi: 10.1038/s41598-020-59510-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The percentage of wound contraction of untreated (IW) and treated groups (M, M-CCH, M-SeNPs, M-SeNPs-CCH) on days 7, 14 and 21. The calculation was performed by ImageJ software. The treating was started on the third day, but it is not included in the figure. *(P ≤ 0.05) shows significant differences between the treated and control groups and #(P ≤ 0.05) between the treated groups by Mann-Whitney test. The data were presented as mean ± SD. The results were obtained based on the triple independent tests (P ≤ 0.05). IW: infectious wound, M: mupirocin, SeNPs: selenium nanoparticles, CCH: Chitosan-N-Cetyl-N,N,N-trimethylammonium bromide-based hydrogel.