Table 1.
Days | Angiogenesis | Fibroblasts | Hair follicle | Epidermis | Collagen | Inflammation | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Groups | 3 | 7 | 14 | 21 | 3 | 7 | 14 | 21 | 3 | 7 | 14 | 21 | 3 | 7 | 14 | 21 | 3 | 7 | 14 | 21 | 3 | 7 | 14 | 21 |
IW | 0 | 1 | 2.2 | 3.9 | 2681 | 3387 | 6570 | 1050 | 0 | 0 | 0 | 0 | 0 | 0 | 12.1 | 39.9 | 0 | 0 | 1.2 | 2.2 | 0 | 1.4 | 1.2 | 1 |
M | 2.4 | 1.5 | 1.4 | 3550 | 12400 | 7680 | 0 | 3 | 5 | 5.3 | 18.7 | 46.8 | 0 | 1.6 | 1.2 | 3.5* | 2.2* | 0.8* | ||||||
M-SeNPs | 3.7 | 3 | 1.3 | 8350 | 3840 | 3200 | 0 | 2 | 5 | 9.7 | 84.5 | 136 | 3.8* | 5.2* | 5.7* | 1 | 0.5 | 0.5 | ||||||
M-CCH | 5.1* | 4.1* | 1* | 13876* | 26650* | 7785 | 0 | 6* | 8* | 35.6* | 142.7* | 184.3* | 2.6 | 4.6 | 3.7 | 1.8 | 1.1 | 0.5 | ||||||
M-SeNPs-CCH | 1.8 | 3.5 | 1.5 | 5510 | 14430 | 12500* | 0 | 3 | 4 | 2.3 | 58.5 | 110 | 0 | 2.2 | 4.9 | 3.7 | 1 | 0.3 |
*Six tissue sections were evaluated for each sample at a set time and the statistical results showed that P-value less than 0.05 was regarded as statistically significant. IW: infectious wound, M: mupirocin, SeNPs: selenium nanoparticle, CCH: chitosan-N-cetyl-N,N,N-trimethylammonium bromide-based hydrogel.