Table 3.
Detailed listing of the type and severity of SAEs designated as being possibly, probably or definitely related to study treatment.
| Toxicity | Observed while taking vismodegib | Maximum grade |
|---|---|---|
| Pancytopeniaa | Yes | 3 |
| Febrile neutropeniab | Yes | 3 |
| Neutrophil count decreasedc | Yes | 3 |
| Platelet count decreasedc | Yes | 3 |
| Pneumonitisb | Yes | 3 |
| Pulmonary drug toxicity | Yes | 3 |
| Dehydration | No | 3 |
| Fevera | No | 2 |
| Pneumonitis | No | 3 |
| Sepsis | No | 3 |
| Anaemiad | No | 3 |
| Dehydrationd | No | 3 |
| Fatigued | No | 2 |
| Liver abscessd | No | 3 |
| Nausead | No | 3 |
| Sepsisd | No | 3 |
| Vomitingd | No | 3 |
| General disorders/administration site conditiond | No | 2 |
a,b,c,dToxicities observed on the same individual
None of these were suspected related to vismodegib