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. 2020 Jan 8;295(7):2018–2033. doi: 10.1074/jbc.RA119.010565

Table 4.

Cardiac function for the Langendorff perfusions

Reported values are just prior to the end of the perfusion. Values are mean ± S.E. *, p < 0.05 versus Beating for the same perfusion duration.

Perfusion duration (min) Beating
Nonbeating
20 (n = 4) 30 (n = 3) 40 (n = 4) 20 (n = 3) 30 (n = 4) 40 (n = 4)
Heart rate (beats/min) 361 ± 10 408 ± 40 423 ± 15 0 ± 0* 0 ± 0* 0 ± 0*
Developed pressure (mm Hg) 22 ± 4 41 ± 22 28 ± 3 0 ± 0* 0 ± 0* 0 ± 0*
+dP/dTmax (mm Hg/s) 1171 ± 279 1791 ± 584 1421 ± 129 0 ± 0* 0 ± 0* 0 ± 0*
−dP/dTmin (mm Hg/s) −831 ± 129 −1294 ± 459 −1009 ± 167 0 ± 0* 0 ± 0* 0 ± 0*
Coronary flow (ml/min) 1.32 ± 0.08 1.76 ± 0.52 1.37 ± 0.03 1.00 ± 0.10* 0.89 ± 0.06 0.90 ± 0.06*
MVO2 (μmol/g wet weight/min) 3.0 ± 0.2 4.1 ± 1.2 2.7 ± 0.2 2.1 ± 0.2* 2.0 ± 0.2 2.0 ± 0.1*