TABLE 2.

Factors explaining variance between overall metabolomic profiles of the adenoma and control groups^a

Factor	Marginal model		Adjusted model
	Variance explained (%)	P value	Variance explained (%)	P value
Group	0.91	0.013	0.91	0.018
Age	1.19	0.156	1.15	0.191
Sex	1.4	0.004	1.4	0.001
Race	1.54	0.323	1.6	0.244
Smoking history	1.03	0.334	0.87	0.627

^aIn the first two columns (under “Marginal model”), percent variance explained by a given factor and the corresponding P value were derived from a marginal model not adjusted for other factors. In the last two columns (under “Adjusted model”), percent variances explained by factors and the corresponding P values were derived from a model adjusted for all factors. PERMANOVA with 999 permutations was used to calculate the P values.