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Virulence of DHN-melanin mutants of three Aspergillus fumigatus strains in a zebrafish model of invasive aspergillosis. (A) Percent survival of zebrafish upon infection with Af293 and the ΔpksP mutant. (B) Percent survival of zebrafish upon infection with CEA17 and the ΔpksP mutant. (C) Percent survival of zebrafish upon infection with IF1SW-F4 and ΔpksP mutant. P values were generated by Cox proportional hazards regression analysis. DPI, days postinfection.
