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. 2019 Dec 6;21:57–65. doi: 10.1016/j.jot.2019.11.001

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© 2019 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(A) Cytotoxicity of micelles against C6 cells after 48 h of incubation; (B) cytotoxicity of micelles against Saos-2 cells after 48 h of incubation. (C) Antitumour activity of DOX-loaded SS-PU-SS-PEG micelles and SS-PU-b-PEG micelles as a function of drug concentration against C6 cells; (D) antitumour activity of DOX-loaded SS-PU-SS-PEG micelles and SS-PU-b-PEG micelles as a function of drug concentration against Saos-2 cells. DOX = doxorubicin; SS-PU-SS-PEG = PEG-sheddable reduction-sensitive polyurethane; SS-PU-b-PEG = PEG-unsheddable reduction-sensitive polyurethane.