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. 2020 Feb 18;5(1):e00684-19. doi: 10.1128/mSystems.00684-19

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Copyright © 2020 Brooks et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Antibiotic resistance profile and whole-genome ML phylogeny of US isolates. (A) Phenotypic susceptibility profile of 50 S. pseudintermedius isolates tested against multiple classes of antibiotics. (B) Whole-genome ML phylogeny of the 50 S. pseudintermedius isolates showing the presence and absence of acquired antibiotic resistance and all four types (type I to IV) of agrD genes. The presence (colored block) and absence (white space) of genes are depicted as a heat map, with color keys explained in the figure. The fluoroquinolone-resistant (FQR) isolates carrying GyrA Ser84Leu plus GrlA Ser80Ile mutations and only GrlA Ser80Ile mutation are shown in red and black, respectively. The FQ-sensitive (FQS) isolates without GyrA and GrlA mutations are shown in green (FQS/FQR column). The STs represented by two or more isolates in our data set are highlighted.