Table 3.
Association between urovirulence genes and susceptibility to antimicrobial agents in P. mirabilis isolates.
| Antibiotics/genes | CIP | CL | NA | SMX | CTX | NFT | NFX | AMP | GN | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| hpmA | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | S | I | R | |
| − | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | |
| + | 43 | 11 | 8 | 33 | 9 | 20 | 27 | 7 | 28 | 25 | 3 | 34 | 61 | 1 | 0 | 1 | 5 | 56 | 51 | 4 | 7 | 23 | 1 | 38 | 44 | 5 | 13 | |
| P value | 0.803 | 0.362 | 0.551 | 0.666 | 0.000 | 0.000 | 0.898 | 0.732 | 0.816 | |||||||||||||||||||
| hpmB | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| + | 44 | 11 | 8 | 33 | 9 | 21 | 27 | 7 | 29 | 25 | 3 | 35 | 61 | 1 | 1 | 2 | 5 | 56 | 52 | 4 | 7 | 23 | 1 | 39 | 45 | 5 | 13 | |
| P value | — | — | — | — | — | — | — | — | — | |||||||||||||||||||
| rsbA | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| + | 44 | 11 | 8 | 33 | 9 | 21 | 27 | 7 | 29 | 25 | 3 | 35 | 61 | 1 | 1 | 2 | 5 | 56 | 52 | 4 | 7 | 23 | 1 | 39 | 45 | 5 | 13 | |
| P value | — | — | — | — | — | — | — | — | — | |||||||||||||||||||
| luxS | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| + | 44 | 11 | 8 | 33 | 9 | 21 | 27 | 7 | 29 | 25 | 3 | 35 | 61 | 1 | 1 | 2 | 5 | 56 | 52 | 4 | 7 | 23 | 1 | 39 | 45 | 5 | 13 | |
| P value | — | — | — | — | — | — | — | — | — | |||||||||||||||||||
| ureC1 | − | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 3 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 |
| + | 43 | 9 | 8 | 33 | 9 | 18 | 27 | 7 | 26 | 24 | 3 | 33 | 59 | 1 | 0 | 1 | 3 | 56 | 49 | 4 | 7 | 23 | 1 | 36 | 42 | 5 | 13 | |
| P value | 0.068 | 0.043 | 0.158 | 0.882 | 0.000 | 0.000 | 0.717 | 0.379 | 0.533 | |||||||||||||||||||
| hlyA | − | 34 | 9 | 5 | 22 | 9 | 17 | 18 | 6 | 24 | 18 | 2 | 28 | 47 | 0 | 1 | 2 | 4 | 42 | 39 | 4 | 5 | 18 | 1 | 29 | 33 | 4 | 11 |
| + | 10 | 2 | 3 | 11 | 0 | 4 | 9 | 1 | 5 | 7 | 1 | 7 | 14 | 1 | 0 | 0 | 1 | 14 | 13 | 0 | 2 | 5 | 0 | 10 | 12 | 1 | 2 | |
| P value | 0.592 | 0.094 | 0.303 | 0.715 | 0.171 | 0.702 | 0.502 | 0.803 | 0.687 | |||||||||||||||||||
| rpoA | − | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 |
| + | 43 | 10 | 8 | 33 | 9 | 19 | 27 | 7 | 27 | 24 | 3 | 34 | 60 | 1 | 0 | 1 | 4 | 56 | 50 | 4 | 7 | 23 | 1 | 37 | 43 | 5 | 13 | |
| P value | 0.442 | 0.127 | 0.298 | 0.921 | 0.000 | 0.000 | 0.804 | 0.530 | 0.662 | |||||||||||||||||||
| atfA | − | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| + | 43 | 11 | 8 | 33 | 9 | 20 | 26 | 7 | 29 | 25 | 2 | 35 | 60 | 1 | 1 | 1 | 5 | 56 | 51 | 4 | 7 | 23 | 1 | 38 | 44 | 5 | 13 | |
| P value | 0.803 | 0.362 | 0.508 | 0.000 | 0.983 | 0.000 | 0.898 | 0.732 | 0.816 | |||||||||||||||||||
| atfC | − | 1 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 3 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 |
| + | 43 | 9 | 8 | 33 | 9 | 18 | 27 | 7 | 26 | 24 | 3 | 33 | 59 | 1 | 0 | 1 | 3 | 56 | 49 | 4 | 7 | 23 | 1 | 36 | 42 | 5 | 13 | |
| P value | 0.068 | 0.043 | 0.158 | 0.882 | 0.000 | 0.000 | 0.717 | 0.379 | 0.533 | |||||||||||||||||||
| mrpA | − | 3 | 1 | 1 | 1 | 1 | 3 | 0 | 1 | 4 | 2 | 1 | 2 | 4 | 0 | 1 | 1 | 1 | 3 | 4 | 0 | 1 | 1 | 0 | 4 | 4 | 0 | 1 |
| + | 41 | 10 | 7 | 32 | 8 | 18 | 27 | 6 | 25 | 23 | 2 | 33 | 57 | 1 | 0 | 1 | 4 | 53 | 48 | 4 | 6 | 22 | 1 | 35 | 41 | 5 | 12 | |
| P value | 0.851 | 0.306 | 0.130 | 0.236 | 0.003 | 0.042 | 0.692 | 0.677 | 0.784 | |||||||||||||||||||
| pm1 | − | 2 | 2 | 1 | 2 | 2 | 1 | 0 | 1 | 4 | 2 | 0 | 3 | 4 | 0 | 1 | 1 | 1 | 3 | 4 | 0 | 1 | 2 | 0 | 3 | 4 | 0 | 1 |
| + | 42 | 9 | 7 | 31 | 8 | 19 | 27 | 6 | 25 | 23 | 3 | 32 | 57 | 1 | 0 | 1 | 4 | 53 | 48 | 4 | 6 | 21 | 1 | 36 | 41 | 5 | 12 | |
| P value | 0.286 | 0.837 | 0.130 | 0.870 | 0.003 | 0.042 | 0.692 | 0.948 | 0.784 | |||||||||||||||||||
Ciprofloxacin: CIP, cephalexin: CL, nalidixic acid: NA, sulfamethoxazole: SMX, ceftriaxone: CTX, nitrofurantoin: NFT, norfloxacin: NFX, ampicillin: AMP, and gentamicin: GN.