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Primary outcome
Boxplots of PBVC by study group at 24 weeks (A) and 96 weeks (B). Horizontal lines are median and IQR; whiskers extend to the minimum and maximum within 1·5 times the IQR; outliers are shown as individual points. Mean PBVC by study group (C), for patients with PBVC data at both 24 and 96 weeks (n=374); whiskers are SD. PBVC=percentage brain volume change.
