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. 2019 Dec 30;27(1):129–137. doi: 10.3233/CBM-190414

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Figure 2. — Receiver Operating Characteristics (ROC) analysis of EDIM-Apo10, EDIM-TKTL1, and combined EDIM score in pancreatic carcinoma, colorectal carcinoma, and cholangiocellular carcinoma ( $n =$ 62) compared with healthy individuals and patient with inflammation ( $n =$ 42). The true positive rates (sensitivity) are plotted as a function of the false positive rate (1 – specificity) for measuring the cut off point; ROC analysis for the diagnosis of pancreatic carcinoma, colorectal carcinoma, and cholangiocellular carcinoma (as GI tumors) shows calculated cut off values with highest diagnostic accuracy of EDIM-Apo10 (cut-off score $>$ 129; sensitivity 0.9180, 95% CI 0.8221–0.9645; specificity 1.000, 95% CI 0.8928–1.000), EDIM TKTL1 (cut-off score $>$ 119; sensitivity 0.9672, 95% CI 0.8881–0.9942; specificity 0.9375, 95% CI 0.7985–0.9889), and combined EDIM (cut-off score $>$ 236; sensitivity 1.000, 95% CI 0.9408–1.000; specificity 0.9615, 95% CI 0.8111–0.9980). Dotted lines show 95% CI.