Table 2.

Recommendations for the evaluation of patients with SMA by the SMArtCARE-project. RULM: revised-upper-limb-module; 6-MWT: six-minute-walking-test

Baseline data (First visit only)
Current medical history and clinical examination
•including WHO motor milestones
Physiotherapeutic assessments:
CHOP INTEND
•All children <2 years of age
•All patients >2 years of age without ability to sit
Bayley-III Scale (motor part)
•Only for children <2 years of age with CHOP INTEND score >50
HFMSE
•All patients >2 years of age with ability to sit
•If CHOP INTEND score >50: CHOP INTEND and HFMSE**
•If CHOP INTEND score >60: HFMSE instead of CHOP INTEND
RULM
•All patients >2 years of age with ability to sit (in a wheelchair)
6-MWT
•All ambulant patients >3 years of age
ALS Functional Rating Scale (in adult patients)
Pulmonary function
Documentation of drug treatment and adverse events