Table 1.
Different types of extracellular vesicles.
| Characteristics | Exosomes | Microvesicles | Apoptotic bodies |
|---|---|---|---|
| Size | 30–100 nm [7] | 50–1000 nm [13] | 1–5000 nm [13] |
| Morphology | Cup-shaped [14] | Heterogeneous [14] | Heterogeneous [14] |
| Origin | Luminal budding into multivesicular bodies (MVBs); release by fusion of MVBs with the cell membrane [13] | Budding off the plasma membrane [15] | Outward blebbing of the cell membrane [13] |
| Composition | Coding RNA, noncoding RNA, proteins, antigen presentation molecules, DNA [10,14] | miRNA, mRNA, proteins, lipids, cytosol [15] | Proteins, lipids, DNA, rRNA, cytosol [15] |