Table 7.

Cox regression analysis

Factors	3-yr univariate Cox		3-yr multivariate Cox
	P value	H (95%CI)	P value	HR (95%CI)
Gender (male vs female)	0.803	1.075 (0.608-1.903)
Age (≥ 60 yr vs < 65 yr)	0.534	0.835 (0.473-1.474)
Lesion location (upper vs middle vs lower)	0.427	1.166 (0.798-1.705)
Tumor size (≥ 3 cm vs < 3 cm)	0.000	3.473 (1.827-6.601)	0.010	2.402 (1.237-4.665)
Differentiation (low differentiation vs moderate + high differentiation)	0.000	3.09 (1.724-5.539)	0.015	2.153 (1.159-4.002)
TNM stage (stage I vs stage II + III)	0.060	0.543 (0.287-1.027)
Adjuvant therapy plan (chemotherapy vs radiotherapy)	0.939	1.025 (0.549-1.911)
Recurrence (recurrence vs non-recurrence)	0.002	2.561 (1.408-4.657)	0.034	1.949 (1.05-3.619)
miR-1304 (high expression vs low expression)	0.001	2.614 (1.448-4.717)	0.036	1.93 (1.044-3.565)