Table 1.

Values defining the maturation map between the default hiPSC-CM and adult base models illustrated in Figure 3.

λNa	2.00	λNaK	-0.16	${\lambda }_{sl}^c$	–0.14
λNaL	-0.08	λCaL	-0.53	${\lambda }_n^s$	–0.10
λKr	-0.54	λbCa	3.90	${\lambda }_d^c$	–0.61
λKs	0.68	λpCa	-0.85	${\lambda }_B^c$	–0.56
λK1	2.23	λNaCa	-0.69	${\lambda }_B^d$	–0.72
λto	8.45	λRyR	-0.20	${\lambda }_B^{sl}$	–0.60
λf	-0.99	λSERCA	-0.53	${\lambda }_B^s$	–0.58
λbCl	42.43	λχ	-0.33

The adult parameters, p^A, are related to the hiPSC-CM parameters, p^hiPSC, by the relation p^A = (1+λ)p^hiPSC. See the sections Modeling the Membrane Currents, Modeling Intracellular Ca²⁺ Dynamics and Section S2.1 in the Supplementary Information for more detailed definitions of each of the λ-values.