Table 2. Overview of beneficiary effects of milk fat globule membrane (MFGM) proteins and polar lipids (20, 27-29).

Component	Potential health effect
Fatty acid-binding protein	Cell growth inhibition Anticancer factor
Butyrophillin	Suppression of multiple sclerosis influences pathogenesis of autistic behaviour
Xanthine dehydrogenase/oxidase	Bactericidal agent Anti-inflammatory action
Breast cancer type 1 susceptibility protein	Inhibition of breast cancer
Breast cancer type 1 susceptibility protein
Sphingolipids and metabolites	Shift in tumour type from malignant to benign Anticholesterolemic protection of the liver from fat- and cholesterol-induced steatosis Suppression of gastrointestinal pathogens (Campylobacter jejuni, Listeria monocytogenes, Clostridium perfrigens, Escherichia coli, Salmonella enteritidis) Neonatal gut maturation Myelination of the developing central nervous system Endogenous modulators of vascular function
Phosphatidylserine	Restoring normal memory of a variety of tasks Positive effects on Alzheimer patients (daily intake 200 mg) Improving exercise capacity of exercising humans
Phosphatidylcholine	Supporting liver recovery from toxic chemical attack or viral damage Protection of the human GI mucosa against toxic attack Reduction of necrotising enterocolitis
Mucins and glycoproteins	Inhibition of Helicobacter pylori Protective effect against rotavirus infections
MFGM hydrolysates	Antimicrobial activity against pathogens