Skip to main content
. 2020 Jan 31;6(1):5–24. doi: 10.2478/jccm-2020-0009

Table 2.

Study Characteristics of 'fair ' quality studies on the impact of intravenous fluid therapy on gut dysfunction.

Author Year Study Population Study
Setting		 Study
type		 Study
patients		 Admission
diagnosis		 Experimental Intravenous
fluid		 Control Intravenous
fluid		 Dindo-Clavien
Classification*
Gan16 2002 major elective general, urologic, or gynaecologic surgery surgery RCT 100 postsurgical 50 GDFT 50 Standard
Moretti1 7 2003 Major elective cardiac surgery surgery RCT 90 postsurgical 30 - HetaStarch normal saline; 30 Heta Starch Balanced
salt; 30 Lactated Ringers
Nisanevich18 2005 elective intraabdominal surgery surgery RCT 157 postsurgical 77 Restrictive 75 Liberal
Kabon19 2005 open colonic resection surgery RCT 253 ICU surgical 124 Small volume 129 Large Volume
Lopes20 2007 High-risk surgery surgery RCT 33 ICU surgical 17 GDFT 16 Control
Vermuelen21 2009 elective major abdominal surgical procedures surgical RCT 62 surgical 30 Restricted 32 Standard
Mayer22 2010 major abdominal surgery surgery RCT 60 ICU surgical 30 GDFT 30 Standard
SAFE 23 2011 ICU ICU RCT 1218 ICU 603 Colloid 615 Crystalloid
Guidet24 2012 severe sepsis ICU RCT 196 ICU 100 Colloid 96 Crystalloid
Perner25 2012 severe sepsis ICU RCT 798 ICU 398 Colloid 400 Crystalloid
Reddy26 2016 critically ill ICU RCT 69 critically ill 35 plasmalyte 34 saline

Abbreviations: GDFT-goal-directed fluid therapy; ICU -intensive care unit; S-ICU -surgical ICU; RCT-randomised controlled trial; * Appendix C