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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Biochim Biophys Acta Biomembr. 2019 Aug 23;1861(12):183051. doi: 10.1016/j.bbamem.2019.183051

Figure 5. Multiple sequence alignment of class A GPCRs from primitive organisms.

Figure 5.

The numbering of residues potentially involved in Na+ coordination is in blue, the numbers of the most conserved residues in each helix are in black. Sequences are listed under their GenBank, UniProt or RefSeq accession numbers, the full list of protein names and organisms is available in Fig. S7 in Supplementary Materials.