Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 18;20:55. doi: 10.1186/s12935-020-1135-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — BRD4 is overexpressed in PC. a Compared to adjacent normal tissues, higher BRD4 mRNA expression in ten fresh samples of PC. The GAPDH expression was detected as the endogenous control. b Representative Immunohistochemical images of BRD4 expression, which was primarily localized in the cell nucleus. Higher BRD4 protein expression was found in PC tissues. c 5 of 7 PC cells lines, including AsPC-1, MIAPaCa-2, PANC-1, SW1990 and CFPAC-1 had higher BRD4 mRNA than levels observed in normal pancreatic ductal epithelial cells HPDE. The GAPDH expression was detected as the endogenous control for mRNA expression. d Higher BRD4 and CAV-2 protein expression in PC cell lines. BRD4 was positive correlated with CAV-2 expression. The asterisk indicates that p is less than 0.05