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. 2020 Feb 18;20:55. doi: 10.1186/s12935-020-1135-0

Table 2.

Correlation between the clinicopathological characteristics and BRD4 and CAV-2 expression in PC

Characteristics N BRD4 level p-value CAV-2 level p-value
Low (26) High (50) Low (34) High (42)
Age (years)
 ≤ 60 23 5 18 0.131 8 15 0.250
 > 60 53 21 32 26 27
Gender
 Male 49 18 31 0.532 22 27 0.970
 Female 27 8 19 12 15
Clinical stage
 Early stages (≤ I) 12 8 4 0.024* 11 1 < 0.001*
 Advanced stages (> I) 64 18 46 23 41
Invasion depth
 T1 + T2 17 8 9 0.205 12 5 0.015*
 T3 + T4 59 18 41 22 37
Lymph nodes metastasis
 N0 (negative) 33 16 17 0.022* 21 12 0.004*
 N1 (positive) 43 10 33 13 30
Distant metastasis
 M0 (absent) 72 25 47 1.000 33 39 0.765
 M1 (present) 4 1 3 1 3
Tumor differentiation
 Well, moderate 51 19 32 0.424 27 24 0.040*
 Poor 25 7 18 7 18
Tumor location
 Head, neck 39 10 29 0.106 14 25 0.112
 Body, tail 37 16 21 20 17
Nervous invasion
 Negative 25 13 12 0.022* 14 11 0.167
 Positive 51 13 38 20 31
Vessel invasion
 Negative 65 26 39 0.025* 32 33 0.112
 Positive 11 0 11 2 9

Asterisk represents the significant difference