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. 2020 Feb 18;18:92. doi: 10.1186/s12967-020-02267-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Immune-related pathways were upregulated in the high glycolysis group. a Top 30 upregulated pathways and seven downregulated pathways in high glycolysis group were obtained by GSEA. The red bars represented the upregulated pathways, while the blue bars showed the downregulated pathways. b GSEA showed that IL-17 signaling pathway was significantly upregulated in high glycolysis group. The value of normalizedEnrichmentScore and FDR were displayed in the figure