Table 1.
Clinical characteristics of 1920 diabetic patients
| Variables | All participants | After PS matching | ||||
|---|---|---|---|---|---|---|
| Obstructive CAD (N = 1054) |
Non-CAD (N = 866) |
Pa | Obstructive CAD (N = 673) |
Non-CAD (N = 673) |
Pa | |
| Age, years | 62.8 ± 9.6 | 61.1 ± 10.7 | < 0.001 | 62.3 ± 9.5 | 62.3 ± 10.8 | 0.977 |
| Male, n (%) | 583 (55.3) | 480 (55.4) | 0.960 | 360 (53.5) | 373 (55.4) | 0.477 |
| BMI, mean (SD), kg/m2 | 25.2 ± 4.0 | 24.3 ± 2.6 | < 0.001 | 24.7 ± 3.9 | 24.5 ± 2.6 | 0.204 |
| BMI categories | ||||||
| Normal | 540 (51.2) | 494 (57.0) | < 0.001 | 412 (61.2) | 396 (58.8) | 0.613 |
| Overweight | 372 (35.3) | 317 (36.6) | 116 (17.2) | 118 (17.6) | ||
| Obese | 142 (13.5) | 55 (6.4) | 145 (21.6) | 159 (23.6) | ||
| Smoking, n (%) | ||||||
| Never smoker | 582 (55.2) | 555 (64.1) | < 0.001 | 382 (56.8) | 358 (53.2) | 0.157 |
| Former smoker | 168 (15.9) | 130 (15.0) | 231 (34.3) | 264 (39.2) | ||
| Current smoker | 304 (28.9) | 181 (20.9) | 60 (8.9) | 51 (7.6) | ||
| Alcohol drinkers, n (%) | 343 (32.5) | 248 (28.6) | 0.065 | 210 (31.2) | 196 (29.1) | 0.406 |
| FPG, mmol/L | 7.3 ± 2.0 | 6.7 ± 1.8 | < 0.001 | 7.0 ± 1.6 | 6.9 ± 2.0 | 0.386 |
| HbA1c, (%) | 8.1 ± 1.8 | 7.9 ± 1.7 | 0.031 | 8.0 ± 1.8 | 8.0 ± 1.7 | 0.779 |
| Diabetes duration, years | 10.3 ± 5.4 | 9.9 ± 5.7 | 0.110 | 10.1 ± 5.4 | 9.7 ± 5.7 | 0.105 |
| Diabetes management | ||||||
| Lifestyle modification | 291 (27.6) | 255 (29.4) | 0.566 | 200 (29.7) | 199 (29.6) | 0.500 |
| Oral agents only | 332 (31.5) | 283 (32.7) | 206 (30.6) | 229 (34.0) | ||
| Insulin only | 275 (26.1) | 214 (24.7) | 166 (24.7) | 157 (23.3) | ||
| Oral agents and insulin | 156 (14.8) | 114 (13.2) | 101 (15.0) | 88 (13.1) | ||
| Dyslipidemia, n (%) | 334 (31.7) | 166 (19.2) | < 0.001 | 164 (24.4) | 158 (23.5) | 0.701 |
| Cholesterol, mmol/L | ||||||
| TC, mmol/L | 4.95 ± 0.91 | 4.80 ± 0.85 | < 0.001 | 4.88 ± 0.90 | 4.85 ± 0.87 | 0.194 |
| LDL-c, mmol/L | 3.28 ± 0.83 | 3.08 ± 0.68 | < 0.001 | 3.16 ± 0.80 | 3.10 ± 0.67 | 0.123 |
| HDL-c, mmol/L | 1.12 ± 0.15 | 1.16 ± 0.21 | 0.318 | 1.09 ± 0.15 | 1.12 ± 0.21 | 0.756 |
| TG, mmol/L | 1.48 ± 0.85 | 1.36 ± 0.76 | 0.104 | 1.49 ± 0.84 | 1.43 ± 0.80 | 0.114 |
| Hypertension, n (%) | 619 (58.7) | 338 (39.0) | < 0.001 | 330 (49.0) | 318 (47.3) | 0.513 |
| Blood pressure | ||||||
| SBP, mmHG | 138.2 ± 21.4 | 134.8 ± 19.5 | < 0.001 | 136.7 ± 25.0 | 135.4 ± 19.1 | 0.157 |
| DBP, mmHG | 88.0 ± 18.4 | 85.1 ± 12.0 | < 0.001 | 86.4 ± 18.1 | 85.9 ± 11.4 | 0.109 |
| CRP, mg/L | 1.57 ± 1.01 | 1.10 ± 0.86 | < 0.001 | 1.34 ± 0.94 | 1.30 ± 0.87 | 0.400 |
| D-dimer, mg/L | 0.98 ± 0.93 | 0.91 ± 0.82 | 0.077 | 0.93 ± 0.95 | 0.91 ± 0.79 | 0.228 |
Data are presented as the mean ± SD or n (%) as appropriate
BMI body mass index, FPG fasting plasma glucose, HbA1c glycosylated haemoglobin, TC total cholesterol, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, TG triglycerides, SBP systolic blood pressure, DBP diastolic blood pressure, CRP C-reactive protein, CAD coronary artery disease, PS propensity score
aP values were obtained from the student t test for continuous variables, and the Pearson χ2 test for categorical variables