Table 1.

DCW, Cell growth rate, l-lysine production, and substrate consumption rate of original strain C. glutamicum K-1 and its derivatives in shake flask experiments

Strains	Sugar
	Glucose				Fructose					Sucrose					Molasses
	DCW	μmax.	PLys	qs	DCW	μmax.	PLys	qs		DCW	μmax.	PLys		qs	DCW	μmax.	PLys	qas
K-1	10.9 ± 1.2	0.25	24.1 ± 1.6	6.26 ± 0.57	8.6 ± 0.5	0.2	17.2 ± 1.8	5.13 ± 0.40		9.9 ± 0.8	0.24	18.9 ± 1.2		5.18 ± 0.32	10.3 ± 1.2	0.2	15.8 ± 2.1	4.38 ± 0.47
K-2	10.6 ± 0.5	0.25	24.3 ± 2.9	6.25 ± 0.66	8.9 ± 0.5	0.21	18.5 ± 1.7	6.06 ± 0.37		10.1 ± 0.6	0.24	23.9 ± 1.6		8.07 ± 0.51	9.8 ± 0.7	0.23	21.3 ± 2.1	7.74 ± 0.45
K-3	1.8 ± 0.2	0.06	0.5 ± 0.06	1.02 ± 0.13	2.1 ± 0.2	0.07	1.3 ± 0.3	1.21 ± 0.05		9.9 ± 1.0	0.23	24.2 ± 1.3		8.06 ± 0.54	9.8 ± 0.3	0.23	22.0 ± 1.8	7.80 ± 0.56
K-4	5.3 ± 0.7	0.12	10.4 ± 1.5	3.38 ± 0.54	9.7 ± 0.6	0.22	23.5 ± 2.2	8.05 ± 0.31		9.8 ± 1.3	0.23	24.1 ± 2.2		8.10 ± 0.72	10.0 ± 1.5	0.24	22.5 ± 1.9	7.95 ± 0.52
K-5	8.9 ± 1.0	0.18	25.3 ± 2.2	7.89 ± 0.71	10.0 ± 1.3	0.22	23.8 ± 3.0	8.06 ± 0.74		9.7 ± 0.9	0.22	24.7 ± 2.7		8.12 ± 0.53	9.8 ± 1.0	0.22	22.8 ± 2.5	7.99 ± 0.63
K-6	10.1 ± 1.4	0.23	26.0 ± 3.0	8.73 ± 0.48	10.2 ± 0.8	0.23	24.9 ± 2.5	8.21 ± 0.57		10.0 ± 1.0	0.23	25.4 ± 1.8		8.33 ± 0.75	9.8 ± 0.6	0.22	23.5 ± 1.5	8.16 ± 0.48
K-7	11.4 ± 1.2	0.26	26.4 ± 1.8	10.62 ± 0.55	10.8 ± 1.3	0.24	25.4 ± 2.1	9.75 ± 0.65		11.1 ± 1.6	0.25	26.0 ± 2.5		9.92 ± 0.49	10.7 ± 0.9	0.24	24.1 ± 2.5	9.72 ± 0.98
K-8	10.8 ± 0.7	0.24	27.6 ± 2.5	11.87 ± 0.34	10.5 ± 0.5	0.24	26.4 ± 2.8	10.92 ± 0.64		10.4 ± 0.9	0.24	27.0 ± 1.9		11.11 ± 0.62	10.5 ± 1.2	0.24	25.2 ± 1.8	10.87 ± 0.74

The culture media was CgXII^IP-medium with 40 g/L of glucose, fructose, beet molasses or 20 g/L of sucrose as sole carbon source

DCW: Dry cell weight (g/L); μ_max.: The maximal specific growth rate (/h); P_Lys: The production of l-lysine (g/L); q_s: The substrate consumption rate (q_s; mmol C/(g DCW)/h)

^aThe data was based on the sucrose consumption rate