Table 4.
Overview on the production of l-lysine by metabolic engineered C. glutamicum
| Strains | Culturing methods | Final titers (g/L) | Productivity (g/L/h) | Yield (g/g glucose) | References |
|---|---|---|---|---|---|
| K-8 | Batch | 27.6 | 0.58 | 0.69 | This work |
| Fed-batch | 221.3 | 5.53 | 0.71 | This work | |
| AM03 | Batch | 27.7 | 0.46 | 0.35 | [60] |
| ZL-92 | Fed-batch | 201.6 | 5.04 | 0.65 | [61] |
| JL‑69Ptac‑Mgdh | Fed-batch | 181.5 | 3.78 | 0.65 | [3] |
| JOV2-C7a | Batch | 13.2 | 0.33 | 0.31 | [62] |
| LYS-12 | Fed-batch | 120 | 4.0 | 0.55 | [10] |
| MH20-22B∆leuAa,b | Batch | 21.6 | 0.3 | 0.22 | [63] |
aAchieved in shake‑flask fermentation
bEstimated from reference