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. 2020 Feb 18;19:39. doi: 10.1186/s12934-020-1294-7

Table 4.

Overview on the production of l-lysine by metabolic engineered C. glutamicum

Strains Culturing methods Final titers (g/L) Productivity (g/L/h) Yield (g/g glucose) References
K-8 Batch 27.6 0.58 0.69 This work
Fed-batch 221.3 5.53 0.71 This work
AM03 Batch 27.7 0.46 0.35 [60]
ZL-92 Fed-batch 201.6 5.04 0.65 [61]
JL‑69Ptac‑Mgdh Fed-batch 181.5 3.78 0.65 [3]
JOV2-C7a Batch 13.2 0.33 0.31 [62]
LYS-12 Fed-batch 120 4.0 0.55 [10]
MH20-22B∆leuAa,b Batch 21.6 0.3 0.22 [63]

aAchieved in shake‑flask fermentation

bEstimated from reference