Table 3.
Associations of eczema phenotypes with allergic sensitization and physician-diagnosed allergies in children at age 10 years
Inhalant sensitization odds ratio (95% CI) |
Food sensitization odds ratio (95% CI) |
Physician-diagnosed inhalant allergy odds ratio (95% CI) |
Physician-diagnosed food allergy odds ratio (95% CI) |
|
---|---|---|---|---|
Never eczema | Reference | Reference | Reference | Reference |
Ever eczema | 2.91(2.41, 3.52) | 4.90 (3.60, 6.67) | 4.54 (3.65, 5.63) | 11.89 (6.85, 20.61) |
Never | Reference | Reference | Reference | Reference |
Early transient | 2.62 (2.01, 3.42) | 5.73 (3.94, 8.31) | 3.72 (2.78, 4.97) | 6.95 (3.76, 12.84) |
Mid-transient | 1.72 (1.25, 2.36) | 2.13 (1.21, 3.76) | 2.66 (1.86, 3.80) | 1.44 (0.43, 4.80) |
Late transient | 1.77 (1.33, 2.35) | 2.52 (1.56, 4.07) | 1.92 (1.34, 2.74) | 4.50 (2.19, 9.28) |
Persistent | 4.53 (2.65, 7.51) | 12.64 (7.20, 22.18) | 11.91 (7.52, 18.86) | 35.05 (18.33, 70.00) |
Values are odds ratios (95% confidence intervals) from logistic regression models for never/ever eczema and average odds ratios (95% confidence intervals) from logistic regression models after multiple sampling based on 150 imputed datasets for eczema phenotypes. Full models were adjusted for parental history of allergy, asthma or eczema, maternal education, parity, child’s sex, ethnicity and breastfeeding. Italic values indicate statistical significance at the α = 0.05 level