Table 1.
Baseline characteristics of CRC and mCRC patients
| Characteristics | CRC patients | mCRC patients |
|---|---|---|
| (N = 8136) | (N = 3878) | |
| Age at diagnosis, year | ||
| Mean (SD) | 59 (13) | 57 (12) |
| Median (IQR) | 60 (50–68) | 58 (49–66) |
| Min - max | 18–96 | 18–96 |
| Age group, n (%) | ||
| 18–49 | 1883 (23%) | 1075 (28%) |
| 50–59 | 2035 (25%) | 1067 (28%) |
| 60+ | 4218 (52%) | 1736 (45%) |
| Gender, n (%) | ||
| Female | 3233 (40%) | 1472 (38%) |
| Male | 4903 (60%) | 2406 (62%) |
| Department of practice, n (%) | ||
| Internal medicine | 7074 (87%) | 3584 (92%) |
| Surgery | 1062 (13%) | 294 (7.6%) |
| Hospital geographic region, n (%) | ||
| North | 489 (6%) | 416 (11%) |
| South | 4972 (61%) | 2258 (58%) |
| East | 533 (6.6%) | 463 (12%) |
| Midwest | 2142 (26%) | 741 (19%) |
| Primary tumor size at diagnosis, centimeters | ||
| Missing, n (%) | 2926 (36%) | 2116 (55%) |
| Mean (SD) | 4.48 (2.05) | 4.52 (2.09) |
| Median (IQR) | 4 (3–5.5) | 4 (3–5.5) |
| Mutation status, n (%) | ||
| KRAS MUT | 794 (10%) | 525 (14%) |
| KRAS WT | 1246 (15%) | 805 (21%) |
| Unknown | 6096 (75%) | 2548 (66%) |
| Primary tumor site at diagnosis, n (%) | ||
| Left-sided | 5751 (71%) | 2659 (69%) |
| Right-sided | 1767 (22%) | 879 (23%) |
| Colorectal NOS | 618 (7.6%) | 340 (8.8%) |
| ECOG PS at diagnosis, n (%) | ||
| Missing, n | 2386 | 1470 |
| 0 | 724 (12%) | 429 (18%) |
| 1 | 4912 (86%) | 1919 (80%) |
| 2 | 65 (1.1%) | 51 (2.1%) |
| 3 | 11 (0.19%) | 7 (0.29%) |
| 4 | 4 (0.07%) | 2 (0.08%) |
Note: CRC colorectal cancer, mCRC metastatic colorectal cancer, SD standard deviation, IQR: interquartile range, min minimum, max maximum, MUT mutation, WT wild-type, NOS not otherwise specified, ECOG PS Eastern Cooperative Oncology Group Performance Status