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Validation that Fgf18CreERT2 behaves as a functional null allele. A-D: Alizarin red and Alcian blue stained whole skeleton of P0 Fgf18CreERT2/CreERT2 and control (Fgf18CreERT2/+) mice showing defects in (A) jaw, (B) calvaria, (C) ribs, and (D) limbs. Arrow indicates a characteristic bend in the radius
