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. Author manuscript; available in PMC: 2020 Feb 19.
Published in final edited form as: Dev Dyn. 2019 Jul 22;248(9):882–893. doi: 10.1002/dvdy.85

FIGURE 4.

FIGURE 4

Fgf18CreERT2 expression in during embryogenesis. A-C: Whole-mount in situ hybridization (WISH) for Fgf18 mRNA in E8.0 (A), E9.5 (B), and E12.5 (C) wild type embryos. D-F: Whole mount eGFP fluorescence in E8.0 (D), E9.5 (E), and E12.5 (F) Fgf18CreERT2/+ embryos. Note: The Fgf18CreERT2 allele contains an eGFP fused upstream of CreERT2. G-I: Whole mount tdTomato fluorescence of mice induced 24 hours before collection at E8.5 (G), E10.5 (H), and E13.5 (I) in Fgf18CreERT2/+; ROSAtdTomato/+ embryos. All embryos are shown laterally and are of the stage indicated. Arrows and brackets indicate localized expression. a, allantois; apsm, anterior presomitic mesoderm; dc, digit condensation; dr, digit ray; drg, dorsal root ganglion; fb, forebrain; fe, femur; lc, Limb paddle condensation; lj, lower jaw; mhb, mid-hindbrain; nt, neural tube; op, otic pit; s, somite or somites; tb, tailbud; tg, trigeminal ganglion