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The role of agrin in stabilizing the tight‐junctional proteins of the BBB. A) Treatment schedule of mice. B) ZO‐1 and VE cadherin detected by confocal microscopy in the ipsilateral cortex (scale bar, 50 µm). The gene expression of ZO‐1 and VE cadherin was measured by PCR using C) gel electrophoresis and D) real‐time PCR in the ischemic penumbra (mean ± SD, n = 3, **p < 0.01).
