Table 2.
IVCY Group (n = 11) | RTX Group (n = 6) | |||||
---|---|---|---|---|---|---|
Active | Remission | P - Value | Active | Remission | P - Value | |
Basic investigations (normal range) | ||||||
WBC (4.00–10.00), ×103/cumm | 20.12 (17.13–38.61)a | 7.55 (4.16–10.91)a | <.001* | 14.77 (10.80–36.62)a | 7.60 (5.11–9.23)a | .007* |
Neutrophils (40.00–74.00), % | 78.23 (±9.92)b | 44.78 (±8.27)b | <.001* | 67.40 (±10.07)b | 52.57 (±9.53)b | .013* |
Hemoglobin (12.00–16.00), g/dL | 9.80 (±1.69)b | 12.40 (±1.34)b | <.001* | 8.75 (±1.95)b | 11.99 (±1.05)b | .050* |
Platelets (140.0–450.0), ×103/cumm | 478.00 (358–654)a | 273.00 (172–412)a | <.001* | 247.00 (105–821)a | 223.00 (179–291)a | .417 |
ESR (4.0–20.0), mm/h | 97.78 (±25.69)b | 47.95 (±18.00)b | <.001* | 91.14 (±11.04)b | 52.00 (±18.99)b | .004* |
C-reactive protein (<5), mg/dL | 37.63 (8.08–272.00)a | 3.34 (1.00–17.63)a | <.001* | 57.45 (4.26–99.28)a | 3.02 (1.59–4.68)a | .009* |
Serum albumin (35–50) (±SD), g/L | 28.85 (±6.44)b | 38.55 (±2.64)b | <.001* | 25.46 (±8.52)b | 35.55 (±1.62)b | .333 |
Alkaline phosphatase (40–150), U/L | 135.0 (83–671)a | 84.5 (36.7–154.0)a | .016* | 405.0 (112.00–1191.0)a | 71.0 (57.0–108.0)a | .012* |
Abbreviations: ESR, erythrocyte sedimentation rate; IQR, interquartile range; IVCY, intravenous cyclophosphamide; RTX, rituximab; WBC, white blood cell count.
aMedian (IQR).
bMean (SD).